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Author Question: If retinoblastoma requires mutation in two copies of the RB gene, and familial cases inherit one ... (Read 38 times)

SAVANNAHHOOPER23

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If retinoblastoma requires mutation in two copies of the RB gene, and familial cases inherit one such mutation, doesn't it seem unlikely that a second mutation would occur in a retinal cell at this specific gene? Yet 90 percent of those individuals who inherit one mutant RB gene develop a second mutation and retinoblastoma. Why does this occur with such a high frequency?


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Marked as best answer by SAVANNAHHOOPER23 on Jul 17, 2021

xiaomengxian

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SAVANNAHHOOPER23

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Reply 2 on: Jul 17, 2021
YES! Correct, THANKS for helping me on my review


chereeb

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Reply 3 on: Yesterday
Excellent

 

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