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Author Question: Which description is consistent with chronic myelogenous leukemia (CML)? (Read 45 times)

chandani

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Which description is consistent with chronic myelogenous leukemia (CML)?

◦ Defects exist in the ras oncogene, TP53 tumor-suppressor gene, and INK4A, the gene encoding a cell-cycle regulatory protein.
◦ Leukocytosis and a predominance of blast cells characterize the bone marrow and peripheral blood. As the immature blasts increase, they replace normal myelocytic cells, megakaryocytes, and erythrocytes.
◦ B cells fail to mature into plasma cells that synthesize immunoglobulins.
◦ The translocation of genetic material from genes 9 and 22 creates an abnormal, fused protein identified as BCR-ABL1.


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Marked as best answer by chandani on Aug 28, 2021

ilianabrrr

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chandani

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Reply 2 on: Aug 28, 2021
YES! Correct, THANKS for helping me on my review


tandmlomax84

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Reply 3 on: Yesterday
:D TYSM

 

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