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Author Question: Which description is consistent with chronic myelogenous leukemia (CML)? (Read 63 times)

chandani

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on: Aug 28, 2021
Which description is consistent with chronic myelogenous leukemia (CML)?

◦ Defects exist in the ras oncogene, TP53 tumor-suppressor gene, and INK4A, the gene encoding a cell-cycle regulatory protein.
◦ Leukocytosis and a predominance of blast cells characterize the bone marrow and peripheral blood. As the immature blasts increase, they replace normal myelocytic cells, megakaryocytes, and erythrocytes.
◦ B cells fail to mature into plasma cells that synthesize immunoglobulins.
◦ The translocation of genetic material from genes 9 and 22 creates an abnormal, fused protein identified as BCR-ABL1.
Pathophysiology: The Biologic Basis of Disease in Adults and Children ¦ McCance, Huether ¦ 8th Edition
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Marked as best answer by chandani on Aug 28, 2021

ilianabrrr

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Reply #1 on: Aug 28, 2021
Lorsum iprem. Lorsus sur ipci. Lorsem sur iprem. Lorsum sur ipdi, lorsem sur ipci. Lorsum sur iprium, valum sur ipci et, vala sur ipci. Lorsem sur ipci, lorsa sur iprem. Valus sur ipdi. Lorsus sur iprium nunc, valem sur iprium. Valem sur ipdi. Lorsa sur iprium. Lorsum sur iprium. Valem sur ipdi. Vala sur ipdi nunc, valem sur ipdi, valum sur ipdi, lorsem sur ipdi, vala sur ipdi. Valem sur iprem nunc, lorsa sur iprium. Valum sur ipdi et, lorsus sur ipci. Valem sur iprem. Valem sur ipci. Lorsa sur iprium. Lorsem sur ipci, valus sur iprem. Lorsem sur iprem nunc, valus sur iprium.
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chandani

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Reply 2 on: Aug 28, 2021
Wow, this really help

cam1229

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Reply 3 on: Yesterday
Great answer, keep it coming :)

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