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There are major differences in the metabolism of morphine and the illegal drug heroin. Morphine mostly produces its CNS effects through m-receptors, and at k- and d-receptors. Heroin has a slight affinity for opiate receptors. Most of its actions are due to metabolism to active metabolites (6-acetylmorphine, morphine, and morphine-6-glucuronide).
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Most childhood vaccines are 90–99% effective in preventing disease. Side effects are rarely serious.
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Women are 50% to 75% more likely than men to experience an adverse drug reaction.
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Bacteria have been found alive in a lake buried one half mile under ice in Antarctica.
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About 100 new prescription or over-the-counter drugs come into the U.S. market every year.