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Autoimmune diseases occur when the immune system destroys its own healthy tissues. When this occurs, white blood cells cannot distinguish between pathogens and normal cells.
In 1864, the first barbiturate (barbituric acid) was synthesized.
Most childhood vaccines are 90–99% effective in preventing disease. Side effects are rarely serious.
Though Candida and Aspergillus species are the most common fungal pathogens causing invasive fungal disease in the immunocompromised, infections due to previously uncommon hyaline and dematiaceous filamentous fungi are occurring more often today. Rare fungal infections, once accurately diagnosed, may require surgical debridement, immunotherapy, and newer antifungals used singly or in combination with older antifungals, on a case-by-case basis.
More than 150,000 Americans killed by cardiovascular disease are younger than the age of 65 years.