Unequal crossing over during prophase I can result in one sister chromosome with a deletion and another with a duplication. A mutated form of hemoglobin, known as hemoglobin Lepore, is known in the human population. Hemoglobin Lepore has a deleted set of amino acids. If it was caused by unequal crossing over, what would be an expected consequence?
A) If it is still maintained in the human population, hemoglobin Lepore must be selected for in evolution.
B) There should also be persons born with, if not living long lives with, an anti-Lepore mutation or duplication.
C) Each of the genes in the hemoglobin gene family must show the same deletion.
D) The deleted gene must have undergone exon shuffling.
E) The deleted region must be located in a different area of the individual's genome.
X chromosome inactivation in female mammals produces the Barr Body.
Phenotypic and molecular markers mapped on human chromosome 1
As a result of this change, deoxyhemoglobin S
the Beta-globin gene subfamily on chromosome 11
Heritable Changes in Chromosome Structure
X chromosome inactivation and its effects