Author Question: What is the best method to prevent warfarin-induced skin necrosis during treatment for thrombosis? ... (Read 62 times)

james · **on:** Jun 25, 2018

What is the best method to prevent warfarin-induced skin necrosis during treatment for thrombosis?

a. Use higher dose of warfarin early in treatment.
b. Give the patient injections of protein C.
c. Stop warfarin at the first sign of necrosis.
d. Use heparin for first 5 days in conjunction with warfarin.

Question 2

Which unusual laboratory finding may be present in sepsis-induced DIC?

a. Fibrinogen may be high because it is an acute phase reactant.
b. Schistocytes are absent because the fever destroys them.
c. D dimer is low because the toxins prevent fibrin lysis.
d. The PT and PTT are low because bacteria interfere with these tests.

johnpizzaz · **Reply #1 on:** Jun 25, 2018

Answer to Question 1

ANS: D
To prevent warfarin-induced skin necrosis, heparin is given along with the warfarin until a therapeutic and stable international normalized ratio (INR) is obtained.

Answer to Question 2

ANS: A
Fibrinogen levels may drop in DIC, but because fibrinogen is an acute phase reactant it may actually be increased in the presence of an inflammatory process such as sepsis.