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Author Question: Which of the following is necessary for platelet adhesion to collagen? a. Calcium b. Fibrinogen ... (Read 37 times)

ts19998

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on: Jun 25, 2018
Which of the following is necessary for platelet adhesion to collagen?
 
  a. Calcium
  b. Fibrinogen
  c. VWF
  d. Factor XIII

Question 2

Which of the following aids in preventing excess clotting?
 
  a. Thrombin
  b. Factor VII
  c. Nitric oxide
  d. Protein C


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Awesome

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Reply #1 on: Jun 25, 2018
Answer to Question 1

ANS: C
VWF is necessary for normal platelet adhesion to exposed subendothelial collagen. Calcium is a cofactor required for binding of vitamin K-dependent proteins to phospholipids. Fibrinogen is necessary for normal platelet aggregation, whereas factor XIII, in its active form, cross-links the fibrin polymer and thus stabilizes the clot.

Answer to Question 2

ANS: D
The protein C pathway helps regulate the coagulation mechanism by digesting activated coagulation factors V and VIII. Thrombin is the activated form of prothrombin; it plays a number of roles in promoting coagulation, including the splitting of fibrinogen to form fibrin. Nitric oxide counteracts vasoconstriction.


ts19998

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Reply 2 on: Jun 25, 2018
:D TYSM

bigcheese9

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Reply 3 on: Yesterday
Great answer, keep it coming :)

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