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Author Question: What is the cause of myelodysplastic syndromes? a. Decreased apoptosis b. Are inherited ... (Read 97 times)

mcmcdaniel

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on: Jun 25, 2018
What is the cause of myelodysplastic syndromes?
 
  a. Decreased apoptosis
  b. Are inherited disorders
  c. Proliferation of mutated myeloid cells
  d. Epstein-Barr virus

Question 2

Which of the following is typical in the peripheral blood in patients with myelodysplastic syndrome?
 
  a. Lymphocytosis
  b. Plasma cells
  c. Hypogranular or agranular neutrophils
  d. Low levels of vitamin B12 or folate


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epscape

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Reply #1 on: Jun 25, 2018
Answer to Question 1

ANS: C
Proliferation of mutated myeloid stem cells is the cause for myelodysplastic syndromes. Apoptosis is increased in early myleodysplastic syndrome, giving rise to the cytopenia (or cytopenias); however, later, if the disease progresses and acute leukemia appears, then apoptosis decreases. They are not inherited, and no association exists with the Epstein-Barr virus.

Answer to Question 2

ANS: C
Maturation of granulocytes is abnormal in several of myelodysplastic syndromes, and as a result hypogranular or agranular neutrophils may be seen.


mcmcdaniel

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Reply 2 on: Jun 25, 2018
Wow, this really help

ktidd

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Reply 3 on: Yesterday
Thanks for the timely response, appreciate it

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