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Author Question: How does lead exposure and the porphyrias cause anemia? a. Cause destruction of red cells b. ... (Read 33 times)

darbym82

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on: Jun 25, 2018
How does lead exposure and the porphyrias cause anemia?
 
  a. Cause destruction of red cells
  b. Chelae iron from the body
  c. Impair iron absorption
  d. Interfere with heme production

Question 2

Which of the following red cell inclusions is or are often found in lead poisoning?
 
  a. Howell-Jolly bodies
  b. Basophilic stippling
  c. Heinz bodies
  d. Cabot rings


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cdmart10

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Reply #1 on: Jun 25, 2018
Answer to Question 1

ANS: D
Common to lead poisoning and the porphyrias is the impairment of protoporphyrin synthesis, which is required for heme production.

Answer to Question 2

ANS: B
Basophilic stippling, sometimes quite coarse, is characteristic of lead poisoning. Lead interferes with the breakdown of pyrimidine 5-nucleotides, which in turn are believed to retard the breakdown of ribosomal ribonucleic acid (RNA), thus leading to stippling.


darbym82

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Reply 2 on: Jun 25, 2018
Great answer, keep it coming :)

FergA

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Reply 3 on: Yesterday
Excellent

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