Phospholipids in the platelet membrane are important for all of ...

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Phospholipids in the platelet membrane are important for all of the following functions except:
 
  a. Supply of arachidonic acid
  b. Receptor for plasma fibrinogen
  c. Receptor for plasma coagulation enzymes
  d. Forms part of the platelet glycocalyx

Question 2

Identify the platelet receptor and plasma protein required for normal platelet aggregation.
 
  Platelet receptor Plasma protein
 
  a. GP IIb/IIIa Fibrinogen
  b. GP IV Factor VIII
  c. GP Ib/IX/V VWF
  d. PF4 Factor V

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Answer to Question 1

ANS: B
Fibrinogen binds to the receptor GP IIb/IIIa. Membrane phospholipids supply arachidonic acid, which becomes converted to thromboxane during platelet activation. They form part of the platelet glycocalyx, which is the platelet surface. Many of the coagulation enzymes bind to platelet phospholipids, including factor IX, X, and prothrombin.

Answer to Question 2

ANS: A
Fibrinogen must bind to its receptor GP IIb/IIIa assembled on the platelet membrane after activation for normal platelet aggregation.

[DelorasTo]

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[nothere]

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