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Author Question: Explain the significance of HLA and ABO antigen compatibility in stem cell transplantation. What ... (Read 76 times)

roselinechinyere27m

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on: Jun 25, 2018
Explain the significance of HLA and ABO antigen compatibility in stem cell transplantation.
 
  What will be an ideal response?

Question 2

Necrotic PMNs in a cytospin can be easily mistaken for which of the following?
 
  a. Nucleated RBCs
  b. Hairy cells
  c. Leukemic blasts
  d. Hypersegmented PMNs


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ultraflyy23

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Reply #1 on: Jun 25, 2018
Answer to Question 1

Answer: Compatibility between donor and recipient is achieved through degrees of HLA compatibility because compatibility is based on the immune system's recognition of certain cell markers as its own (self). ABO compatibility is not needed because the ABO antigens are not expressed on HSCs.

Answer to Question 2

Correct Answer: A


roselinechinyere27m

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Reply 2 on: Jun 25, 2018
Thanks for the timely response, appreciate it

kishoreddi

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Reply 3 on: Yesterday
Excellent

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