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Author Question: A 45-year-old female was evaluated by her physician because she had unexplained bruising on her ... (Read 115 times)

sdfghj

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on: Jun 25, 2018
A 45-year-old female was evaluated by her physician because she had unexplained bruising on her upper torso. Patient history was unremarkable. Physical examination revealed a palpable liver and spleen. CBC results revealed:
 
  WBC count: 12 x 109/L
  Hb: 8.7 g/dL
  Hct: 25
  Normal indices
  PLT count: 5 x 109/L
  Differential: 80 blasts and 15 promyelocytes present
  Bone marrow findings: hypercellular marrow with 47 myeloblasts present. Nucleated erythroblasts: 22; promyelocytes: 28; megakaryopoiesis appears normal.
  Cytogenetic analysis: t(15, 17) present.
 
  Flow cytometry has also been ordered on this patient. Which of the following markers will stain positive in this case?
  a. HLA-DR
  b. CD35
  c. CD33
  d. CD8

Question 2

A patient presents with a morphological smear examination revealing >20 blasts with prominent granules and Auer rods, MPO, and SBB positive. A 25 monocyte count was seen in the peripheral smear.There were no recurrent cytogenetic abnormalities observ
 
  Under which classification of acute leukemia, not otherwise specific, does this diagnosis fall?
 
  a. Acute myeloblastic leukemia without maturation
  b. Acute myelomonocytic leukemia
  c. Acute erythroid leukemia
  d. Acute panmyelosis with myelofibrosis


234sdffa

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Reply #1 on: Jun 25, 2018
Answer to Question 1

Correct Answers: C

Answer to Question 2

Correct Answer: B


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sdfghj

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Reply #2 on: Jun 25, 2018
Thank you


234sdffa

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Reply #3 on: Jun 25, 2018
No problemo


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