This topic contains a solution. Click here to go to the answer
« previous next »

Author Question: Explain the pathophysiology of MDS. What will be an ideal ... (Read 67 times)

bcretired

  • Hero Member
  • *****
  • Posts: 525
on: Jun 25, 2018
Explain the pathophysiology of MDS.
 
  What will be an ideal response?

Question 2

Give at least five morphologic indicators of dyserythropoiesis.
 
  What will be an ideal response?


Related Topics

Need homework help now?

Ask unlimited questions for free

Ask a Question
Marked as best answer by a Subject Expert

Anonymous

  • Sr. Member
  • ****
  • Posts: 317
Reply #1 on: Jun 25, 2018
Answer to Question 1

Answer: MDS results from persistent gradual expansion of abnormal hematopoietic stem cells that leads to ineffective hematopoiesis. Chromosomal abnormalities accompany the MDS pathogenesis >50 of the time.

Answer to Question 2

Answer: Evidence of dyserythropoiesis in peripheral circulation includes anemia, macrocytosis, oval macrocytes, dimorphism, Howell-Jolly bodies, NRBCs, basophilic stippling, anisocytosis, poikilocytosis, and reticulocytopenia. Evidence of dyserythropoiesis in the bone marrow includes megaloblastoid erythropoiesis, nuclear fragmentation and budding, karyorrhexis, multinucleation, defective hemoglobinization, vacuolization, and ringed sideroblasts.


bcretired

  • Hero Member
  • *****
  • Posts: 525
Reply #2 on: Jun 25, 2018
Correct answers!


Anonymous

  • Sr. Member
  • ****
  • Posts: 317
Reply #3 on: Jun 25, 2018
Great! Please up vote :D


« previous next »
 

Did you know?

The most destructive flu epidemic of all times in recorded history occurred in 1918, with approximately 20 million deaths worldwide.

Did you know?

There are major differences in the metabolism of morphine and the illegal drug heroin. Morphine mostly produces its CNS effects through m-receptors, and at k- and d-receptors. Heroin has a slight affinity for opiate receptors. Most of its actions are due to metabolism to active metabolites (6-acetylmorphine, morphine, and morphine-6-glucuronide).

Did you know?

Certain rare plants containing cyanide include apricot pits and a type of potato called cassava. Fortunately, only chronic or massive ingestion of any of these plants can lead to serious poisoning.

Did you know?

When blood is deoxygenated and flowing back to the heart through the veins, it is dark reddish-blue in color. Blood in the arteries that is oxygenated and flowing out to the body is bright red. Whereas arterial blood comes out in spurts, venous blood flows.

Did you know?

The Food and Drug Administration has approved Risperdal, an adult antipsychotic drug, for the symptomatic treatment of irritability in children and adolescents with autism. The approval is the first for the use of a drug to treat behaviors associated with autism in children. These behaviors are included under the general heading of irritability and include aggression, deliberate self-injury, and temper tantrums.

Pathophysiology of heart failure Pathophysiology of heart failure
A pharmacist can explain to a patient why medication may look different and ensure the correct ... A pharmacist can explain to a patient why medication may look different and ensure the correct ...
Draw and label a diagram and explain how a factor-dependent transcription (rho-dependent) terminator Draw and label a diagram and explain how a factor-dependent transcription (rho-dependent) terminator
Mechanisms to Explain the Effects of Massage Mechanisms to Explain the Effects of Massage
Pathophysiology of heart failure Pathophysiology of heart failure
For the circuit in Figure 1, assume ideal diodes. The peak inverse voltage is approximately For the circuit in Figure 1, assume ideal diodes. The peak inverse voltage is approximately
Video: Types of synapses - electrical & chemical

For a complete list of videos, visit our video library