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Author Question: What are three defining characteristics that would help the laboratory professional differentiate ... (Read 91 times)

pane00

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on: Jun 25, 2018
What are three defining characteristics that would help the laboratory professional differentiate between a blast and an activated lymphocyte?
 
  What will be an ideal response?

Question 2

What is the difference between polyclonal antibodies and monoclonal antibodies? List examples of disorders that generate each type of antibody in your answer.
 
  What will be an ideal response?


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234sdffa

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Reply #1 on: Jun 25, 2018
Answer to Question 1

Answer: Blasts: high N:C ratio; large cell; open chromatin pattern with prominent nucleoli; scanty basophilic cytoplasm
Activated lymphocyte: Low N:C ratio; large, but may be variable sized cell; more clumped chromatin and oval-shaped nucleus; abundant cytoplasm with basophilic rim; kiss other cells producing a scalloped cell shape

Answer to Question 2

Answer: Polyclonal antibodies are in a group of heterogeneous antibodies with multiple antigenic specificities. Monoclonal antibodies have a single specificity. Multiple myeloma generates monoclonal antibodies; infectious mononucleosis generates polyclonal antibodies.


pane00

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Reply 2 on: Jun 25, 2018
Thanks for the timely response, appreciate it

mcabuhat

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Reply 3 on: Yesterday
Great answer, keep it coming :)

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