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Lower drug doses for elderly patients should be used first, with titrations of the dose as tolerated to prevent unwanted drug-related pharmacodynamic effects.
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The longest a person has survived after a heart transplant is 24 years.
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Throughout history, plants containing cardiac steroids have been used as heart drugs and as poisons (e.g., in arrows used in combat), emetics, and diuretics.
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In 1864, the first barbiturate (barbituric acid) was synthesized.
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Human stomach acid is strong enough to dissolve small pieces of metal such as razor blades or staples.