Author Question: Which population is at highest risk for the occurrence of aneuploidy in offspring? A. Mothers ... (Read 29 times)

lak · **on:** Jun 25, 2018

Which population is at highest risk for the occurrence of aneuploidy in offspring?

A. Mothers younger than 18
B. Fathers younger than 18
C. Mothers over age 35
D. Fathers over age 35

Question 2

The pedigree of a family with a mitochondrial DNA disorder is unique in that:

A. None of the female offspring will have the disease
B. All offspring from an affected female will have disease
C. None of the offspring of an affected female will have the disease
D. All the offspring from an affected male will have disease

debra928 · **Reply #1 on:** Jun 25, 2018

Answer to Question 1

ANS: C
Some individuals or couples have unique identifiable risks that should be discussed prior to conception whenever possible. For example, women who will be 35 years of age or older at delivery (advanced maternal age) are at increased risk for aneuploidy.

Answer to Question 2

ANS: B
Mitochondrial DNA is inherited from the ovum and, therefore, from the mother. The pedigree of a family with a mitochondrial DNA disorder is unique in that all offspring (regardless of gender) of an affected female will have the disease, and none of the offspring from an affected male will have the disease.