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There are major differences in the metabolism of morphine and the illegal drug heroin. Morphine mostly produces its CNS effects through m-receptors, and at k- and d-receptors. Heroin has a slight affinity for opiate receptors. Most of its actions are due to metabolism to active metabolites (6-acetylmorphine, morphine, and morphine-6-glucuronide).
This year, an estimated 1.4 million Americans will have a new or recurrent heart attack.
The modern decimal position system was the invention of the Hindus (around 800 AD), involving the placing of numerals to indicate their value (units, tens, hundreds, and so on).
Bacteria have been found alive in a lake buried one half mile under ice in Antarctica.
In 1864, the first barbiturate (barbituric acid) was synthesized.