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Women are two-thirds more likely than men to develop irritable bowel syndrome. This may be attributable to hormonal changes related to their menstrual cycles.
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Most childhood vaccines are 90–99% effective in preventing disease. Side effects are rarely serious.
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More than 150,000 Americans killed by cardiovascular disease are younger than the age of 65 years.
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Disorders that may affect pharmacodynamics include genetic mutations, malnutrition, thyrotoxicosis, myasthenia gravis, Parkinson's disease, and certain forms of insulin-resistant diabetes mellitus.
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More than nineteen million Americans carry the factor V gene that causes blood clots, pulmonary embolism, and heart disease.