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Cocaine was isolated in 1860 and first used as a local anesthetic in 1884. Its first clinical use was by Sigmund Freud to wean a patient from morphine addiction. The fictional character Sherlock Holmes was supposed to be addicted to cocaine by injection.
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It is difficult to obtain enough calcium without consuming milk or other dairy foods.
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After 5 years of being diagnosed with rheumatoid arthritis, one every three patients will no longer be able to work.
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There are 60,000 miles of blood vessels in every adult human.
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Lower drug doses for elderly patients should be used first, with titrations of the dose as tolerated to prevent unwanted drug-related pharmacodynamic effects.