A young boy will receive a bone marrow transplant (BMT). This is ...

[Bob-Dole]

A young boy will receive a bone marrow transplant (BMT). This is possible because one of his older siblings is a histocompatible donor. This type of BMT is termed:
 
  a. Syngeneic. c. Monoclonal.
  b. Allogeneic. d. Autologous.

Question 2

What is most descriptive of the pathophysiology of leukemia?
 
  a. Increased blood viscosity occurs.
  b. Thrombocytopenia (excessive destruction of platelets) occurs.
  c. Unrestricted proliferation of immature white blood cells (WBCs) occurs.
  d. The first stage of the coagulation process is abnormally stimulated.

[xMRAZ]

Answer to Question 1

ANS: B
Allogeneic transplants are from another individual. Because he and his sibling are histocompatible, the bone marrow transplantation can be done. Syngeneic marrow is from an identical twin. There is no such thing as a monoclonal bone marrow transplant. Autologous refers to the individual's own marrow.

Answer to Question 2

ANS: C
Leukemia is a group of malignant disorders of the bone marrow and the lymphatic system. It is defined as an unrestricted proliferation of immature WBCs in the blood-forming tissues of the body. Increased blood viscosity may occur secondary to the increased number of WBCs. Thrombocytopenia may occur secondary to the overproduction of WBCs in the bone marrow. The coagulation process is unaffected by leukemia.

[Bob-Dole]

Excellent

[tuate]

TYSM