Author Question: What pain medication is contraindicated in children with sickle cell disease (SCD)? a. Meperidine ... (Read 18 times)

jon_i · **on:** Jun 28, 2018

What pain medication is contraindicated in children with sickle cell disease (SCD)?

a. Meperidine (Demerol)
b. Hydrocodone (Vicodin)
c. Morphine sulfate
d. Ketorolac (Toradol)

Question 2

What condition is an inherited immunodeficiency disorder characterized by absence of both humoral and cell-mediated immunity?

a. Fanconi syndrome
b. Wiskott-Aldrich syndrome
c. Acquired immunodeficiency syndrome (AIDS)
d. Severe combined immunodeficiency syndrome (SCIDS)

frogdreck123456 · **Reply #1 on:** Jun 28, 2018

Answer to Question 1

ANS: A
Meperidine (pethidine Demerol) is not recommended. Normeperidine, a metabolite of meperidine, is a central nervous system stimulant that produces anxiety, tremors, myoclonus, and generalized seizures when it accumulates with repetitive dosing. Patients with SCD are particularly at risk for normeperidine-induced seizures.

Answer to Question 2

ANS: D
SCIDS is a genetic disorder that results in deficits of both humoral and cellular immunity. Fanconi syndrome is a hereditary disorder of red blood cell production. Wiskott-Aldrich syndrome is an X-linked recessive disorder with selected deficiencies of T and B lymphocytes. AIDS is not inherited.