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The first oncogene was discovered in 1970 and was termed SRC (pronounced "SARK").
Long-term mental and physical effects from substance abuse include: paranoia, psychosis, immune deficiencies, and organ damage.
In ancient Rome, many of the richer people in the population had lead-induced gout. The reason for this is unclear. Lead poisoning has also been linked to madness.
Many supplement containers do not even contain what their labels say. There are many documented reports of products containing much less, or more, that what is listed on their labels. They may also contain undisclosed prescription drugs and even contaminants.
More than 2,500 barbiturates have been synthesized. At the height of their popularity, about 50 were marketed for human use.