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There are major differences in the metabolism of morphine and the illegal drug heroin. Morphine mostly produces its CNS effects through m-receptors, and at k- and d-receptors. Heroin has a slight affinity for opiate receptors. Most of its actions are due to metabolism to active metabolites (6-acetylmorphine, morphine, and morphine-6-glucuronide).
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Medication errors are three times higher among children and infants than with adults.
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By definition, when a medication is administered intravenously, its bioavailability is 100%.
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More than 150,000 Americans killed by cardiovascular disease are younger than the age of 65 years.
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Excessive alcohol use costs the country approximately $235 billion every year.