Author Question: An example of a drug that may receive expedited medical approval would be: a. A drug used to ... (Read 133 times)

panfilo · **on:** Jul 3, 2018

An example of a drug that may receive expedited medical approval would be:

a. A drug used to treat a rare disease that affects less than 200,000 people
b. A placebo that is administered to provide psychological control of responses
c. A drug that may help prevent a public health threat such as HIV
d. A drug that is being evaluated in order to determine the therapeutic index

Question 2

Which of the following statements regarding colloid statements is TRUE?

a. Colloids readily diffuse into the extravascular space for fluid replacement.
b. Colloids exert osmotic pressures that draw fluids into the vascular space for volume replacement.
c. Colloids do not contain proteins or sugars; therefore they do not make suitable solutions for volume replacement.
d. Colloids are inexpensive, have and long shelf-life, and are widely used among most EMS communities.

Hikerman221 · **Reply #1 on:** Jul 3, 2018

Answer to Question 1

c
Rationale: a. This answer describes the definition of an orphan drug.
b. A placebo is used in testing and does not require expedited medical approval.
c. Expedited approval may be granted when a drug may be of use in treating a public health threat such as HIV.
d. The therapeutic index is obtained during preclinical phase of drug testing and does not require expedited approval.

Answer to Question 2

b
Rationale: a. Due to the large molecular size and weight, colloids remain in the vascular space.
b. Correct.
c. Colloids are generally protein-containing solutions, or have large sugar molecules (such as Dextran) and are suitable volume expanders.
d. Colloids are expensive, have a short shelf-life, and are infrequently used in the EMS community.