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Bisphosphonates were first developed in the nineteenth century. They were first investigated for use in disorders of bone metabolism in the 1960s. They are now used clinically for the treatment of osteoporosis, Paget's disease, bone metastasis, multiple myeloma, and other conditions that feature bone fragility.
The familiar sounds of your heart are made by the heart's valves as they open and close.
In 1885, the Lloyd Manufacturing Company of Albany, New York, promoted and sold "Cocaine Toothache Drops" at 15 cents per bottle! In 1914, the Harrison Narcotic Act brought the sale and distribution of this drug under federal control.
The immune system needs 9.5 hours of sleep in total darkness to recharge completely.
Egg cells are about the size of a grain of sand. They are formed inside of a female's ovaries before she is even born.