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Signs of depression include feeling sad most of the time for 2 weeks or longer; loss of interest in things normally enjoyed; lack of energy; sleep and appetite disturbances; weight changes; feelings of hopelessness, helplessness, or worthlessness; an inability to make decisions; and thoughts of death and suicide.
Pope Sylvester II tried to introduce Arabic numbers into Europe between the years 999 and 1003, but their use did not catch on for a few more centuries, and Roman numerals continued to be the primary number system.
On average, the stomach produces 2 L of hydrochloric acid per day.
Increased intake of vitamin D has been shown to reduce fractures up to 25% in older people.
The heart is located in the center of the chest, with part of it tipped slightly so that it taps against the left side of the chest.