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Cucumber slices relieve headaches by tightening blood vessels, reducing blood flow to the area, and relieving pressure.
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Sildenafil (Viagra®) has two actions that may be of consequence in patients with heart disease. It can lower the blood pressure, and it can interact with nitrates. It should never be used in patients who are taking nitrates.
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In 1844, Charles Goodyear obtained the first patent for a rubber condom.
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The word drug comes from the Dutch word droog (meaning "dry"). For centuries, most drugs came from dried plants, hence the name.
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In 1864, the first barbiturate (barbituric acid) was synthesized.