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In most cases, kidneys can recover from almost complete loss of function, such as in acute kidney (renal) failure.
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Disorders that may affect pharmacodynamics include genetic mutations, malnutrition, thyrotoxicosis, myasthenia gravis, Parkinson's disease, and certain forms of insulin-resistant diabetes mellitus.
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Thyroid conditions may make getting pregnant impossible.
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There are 60,000 miles of blood vessels in every adult human.
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People with alcoholism are at a much greater risk of malnutrition than are other people and usually exhibit low levels of most vitamins (especially folic acid). This is because alcohol often takes the place of 50% of their daily intake of calories, with little nutritional value contained in it.