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There are major differences in the metabolism of morphine and the illegal drug heroin. Morphine mostly produces its CNS effects through m-receptors, and at k- and d-receptors. Heroin has a slight affinity for opiate receptors. Most of its actions are due to metabolism to active metabolites (6-acetylmorphine, morphine, and morphine-6-glucuronide).
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The ratio of hydrogen atoms to oxygen in water (H2O) is 2:1.
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There are over 65,000 known species of protozoa. About 10,000 species are parasitic.
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The first documented use of surgical anesthesia in the United States was in Connecticut in 1844.
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The first war in which wide-scale use of anesthetics occurred was the Civil War, and 80% of all wounds were in the extremities.