Funding has been secured to test the efficacy of a new antidepressant. Participants who have been diagnosed with depression have been recruited and randomly assigned to experimental and control groups.
Members of both groups have had the severity of their depression gauged by a reliable and valid instrument. Over the next several weeks, the experimental group has been administered the new drug while the control group received standard treatment. At the completion of the study, the same instrument was used to measure depressive symptoms. Which of the following study designs has the research team utilized?
A) Two-group RCT with pretest/posttest
B) Two-group RCT with true control group
C) Two-group RCT with long-term repeated measures
D) Two-group RCT with posttest design only
Question 2
When reviewing the studies that were included in a systematic review, a nurse is aware of the potential for publication bias. What is an implication of this phenomenon?
A) Studies with no demonstrated effect may not appear in the literature.
B) Studies that challenge accepted practice are often rejected for publication.
C) The fact that a study has been published constitutes a form of bias.
D) Biased publications often form the basis of accepted practice.
Antidepressant Therapy Is Directed Toward the Amelioration of Depressive Symptoms
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