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In 1844, Charles Goodyear obtained the first patent for a rubber condom.
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Between 1999 and 2012, American adults with high total cholesterol decreased from 18.3% to 12.9%
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Approximately 70% of expectant mothers report experiencing some symptoms of morning sickness during the first trimester of pregnancy.
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There are major differences in the metabolism of morphine and the illegal drug heroin. Morphine mostly produces its CNS effects through m-receptors, and at k- and d-receptors. Heroin has a slight affinity for opiate receptors. Most of its actions are due to metabolism to active metabolites (6-acetylmorphine, morphine, and morphine-6-glucuronide).
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The first documented use of surgical anesthesia in the United States was in Connecticut in 1844.