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Bisphosphonates were first developed in the nineteenth century. They were first investigated for use in disorders of bone metabolism in the 1960s. They are now used clinically for the treatment of osteoporosis, Paget's disease, bone metastasis, multiple myeloma, and other conditions that feature bone fragility.
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Women are 50% to 75% more likely than men to experience an adverse drug reaction.
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Human stomach acid is strong enough to dissolve small pieces of metal such as razor blades or staples.
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It is difficult to obtain enough calcium without consuming milk or other dairy foods.
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Russia has the highest death rate from cardiovascular disease followed by the Ukraine, Romania, Hungary, and Poland.