The nurse cautions the older adult who is taking the protein-bound drug warfarin (Coumadin) that, with age-related reduced plasma protein levels, the risk of an adverse reaction is high because:
a. unbound active drug molecules continue to circulate in the bloodstream.
b. the bleeding and clotting time will decrease, as evidenced by the PT and INR.
c. the drug becomes ineffective and does not deliver its intended therapeutic action.
d. renal damage can occur from the altered drug molecules.
Question 2
The nurse takes into consideration that as adipose tissue replaces muscle mass in the older adult, a person taking a fat-soluble drug such as diazepam (Valium) several times a day would exhibit:
a. tachycardia.
b. a hangover effect.
c. agitation.
d. hypertension.
Common Health Problems in Community-Dwelling Older Adults
Serotonin and Risk-Taking Behavior
RNA and Protein Evolution
The Drug Development Process
Children and adolescents define themselves as they get older