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Lower drug doses for elderly patients should be used first, with titrations of the dose as tolerated to prevent unwanted drug-related pharmacodynamic effects.
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The average adult has about 21 square feet of skin.
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More than 2,500 barbiturates have been synthesized. At the height of their popularity, about 50 were marketed for human use.
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Alcohol acts as a diuretic. Eight ounces of water is needed to metabolize just 1 ounce of alcohol.
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Medication errors are three times higher among children and infants than with adults.