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Though Candida and Aspergillus species are the most common fungal pathogens causing invasive fungal disease in the immunocompromised, infections due to previously uncommon hyaline and dematiaceous filamentous fungi are occurring more often today. Rare fungal infections, once accurately diagnosed, may require surgical debridement, immunotherapy, and newer antifungals used singly or in combination with older antifungals, on a case-by-case basis.
Human stomach acid is strong enough to dissolve small pieces of metal such as razor blades or staples.
In 1864, the first barbiturate (barbituric acid) was synthesized.
The immune system needs 9.5 hours of sleep in total darkness to recharge completely.
In 1844, Charles Goodyear obtained the first patent for a rubber condom.