Answer to Question 1
The adverse environmental problems that can occur as a result of pesticide use include the development of resistance by pests, resurgence, and secondary pest outbreaks. The adverse human health effects include chronic effects such as cancer dermatitis, neurological disorder, birth defects, and infertility. Additionally, immune suppression is possible, along with disruption of the endocrine system.
Answer to Question 2
DDT appeared to be nothing less than the long-sought magic bullet,' a chemical that was extremely toxic to insects yet seemed nontoxic to humans and other mammals. It was inexpensive to produce. It was broad spectrum, meaning that it was effective against a multitude of insect pests. It was also persistent, meaning that it did not break down readily in the environment and hence provided lasting protection.
Stereoisomers have different effects in humans
Handbook of Informatics for Nurses and Health Care Professionals, 4/E
Bandura's social-cognitive model of human behaviour
Misfolding or refolding of some proteins can result in disease
Human Genetic Disorders
Mutations in human mitochondrial genes leading to disease syndromes