What was the outcome of a study conducted by Gross et al using ...

[Yolanda]

What was the outcome of a study conducted by Gross et al using heliox on mechanically ventilated infants with bronchiolitis?
 
  A. Heliox improved pulmonary compliance.
  B. Heliox reduced airway resistance.
  C. No improvement in gas exchange occurred from breathing heliox.
  D. Length of stay in the ICU was less because of heliox.

Question 2

What has been the evidence for the use of heliox during mechanical ventilation in patients with COPD exacerbations?
 
  A. The data are inconclusive.
  B. Results reveal that heliox lowers the Pplateau and reduces auto-PEEP.
  C. Heliox has shown to decrease pulmonary compliance and to decrease airway resistance.
  D. Evidence indicates heliox has no effect on the outcome regarding mechanically ventilated COPD patients.

[mbcrismon]

Answer to Question 1

ANS: C
A. Incorrect response: See explanation C.
B. Incorrect response: See explanation C.
C. Correct response: Gross et al assessed the response to heliox in a case series involving 10 mechanically ventilated infants with bronchiolitis. Heliox did not improve gas exchange during mechanical ventilation, and no significant changes in Pao2 or Paco2 were noted.
D. Incorrect response: See explanation C.

Answer to Question 2

ANS: A
A. Correct response: The evidence for the use of heliox in patients with COPD exacerbations is not robust or mature. Most of the peer-reviewed literature consists of case reports, case series, and physiologic studies in small samples of carefully selected patients. Even in the physiologic studies, a consistent response is not reported in all patients. Some patients with COPD exacerbations have a favorable physiologic response to heliox therapy, whereas others do not, and predicting who will be a responder and who will not is difficult.
B. Incorrect response: See explanation A.
C. Incorrect response: See explanation A.
D. Incorrect response: See explanation A.

[Yolanda]

Excellent

[samiel-sayed]

TYSM