A patient with which of the following diseases will have the ...

[burchfield96]

A patient with which of the following diseases will have the longest life expectancy?
 
  a. Alveolar proteinosis
  b. Idiopathic pulmonary fibrosis
  c. Nonspecific interstitial pneumonitis
  d. Sarcoidosis

Question 2

Which of the interstitial lung diseases will in one-third of patients cause a chylothorax?
 
  a. Alveolar proteinosis
  b. Idiopathic pulmonary fibrosis
  c. Lymphangioleiomyoma tosis
  d. Nonspecific interstitial pneumonitis

[amandalm]

Answer to Question 1

ANS: D
Although the prognosis for NSIP is better than IPF, the life expectancy is still only 7 to 10 years. Sarcoidosis often follows a benign course without symptoms or long-term consequences and may spontaneously resolve.

Answer to Question 2

ANS: C
Lymphangioleiomyoma tosis (LAM) is a rare disorder of abnormal smooth muscle tissue prolifer-ating around small airways leading to severe obstruction and destruction of alveoli with resultant thin-walled cyst formation. Unilateral or less commonly bilateral chylothorax is seen in approxi-mately one-third of patients. This results from lymphatic obstruction by abnormal smooth muscle tissue.