Answer to Question 1
ANS: A
Leukotrienes are mediators of inflammation and bronchoconstriction and are thought to play a role in the pathogenesis of asthma. Three leukotriene antagonists are currently available for the treatment of asthma.
Answer to Question 2
ANS: C
The effectiveness of beta-2 agonists as bronchodilators is not disputed, and they remain the drug of choice for acute emergency management of asthma. However, there is concern that they may worsen asthma control if used regularly and that excessive use may increase the risk of death from asthma, which makes their role in long-term maintenance therapy questionable