This topic contains a solution. Click here to go to the answer
« previous next »

Author Question: DNA helicase inhibitors are well studied as potential drug targets. What would you expect to seeif ... (Read 17 times)

CORALGRILL2014

  • Hero Member
  • *****
  • Posts: 525
on: Jan 12, 2022
DNA helicase inhibitors are well studied as potential drug targets. What would you expect to see 
if DNA helicase activity is inhibited?
◦ The replisome complex would not assemble on the oriC region.
◦ The DNA cannot bend, so hydrogen bonds in the 13-mer region of oriC remain intact.
◦ Helicase catalyzes ATP hydrolysis and DNA strands separation, so the helix cannot be unwound and strands will not separate.
◦ Helicase carries the SSB protein to the open region of DNA, so hydrolysis and strand separation will not occur.
◦ Helicase prevents reannealing of the separated strands, so strands would quickly reanneal and DNA replication cannot proceed.
Genetic Analysis: An Integrated Approach ¦ Sanders, Bowman ¦ 3rd Edition
Buy Test-Bank


Related Topics

Need homework help now?

Ask unlimited questions for free

Ask a Question
Marked as best answer by CORALGRILL2014 on Jan 12, 2022

ansleighelindsey

  • Sr. Member
  • ****
  • Posts: 364
Reply #1 on: Jan 12, 2022
Lorsum iprem. Lorsus sur ipci. Lorsem sur iprem. Lorsum sur ipdi, lorsem sur ipci. Lorsum sur iprium, valum sur ipci et, vala sur ipci. Lorsem sur ipci, lorsa sur iprem. Valus sur ipdi. Lorsus sur iprium nunc, valem sur iprium. Valem sur ipdi. Lorsa sur iprium. Lorsum sur iprium. Valem sur ipdi. Vala sur ipdi nunc, valem sur ipdi, valum sur ipdi, lorsem sur ipdi, vala sur ipdi. Valem sur iprem nunc, lorsa sur iprium. Valum sur ipdi et, lorsus sur ipci. Valem sur iprem. Valem sur ipci. Lorsa sur iprium. Lorsem sur ipci, valus sur iprem. Lorsem sur iprem nunc, valus sur iprium.
Answer Preview
Only 45% of students answer this correctly


CORALGRILL2014

  • Member
  • Posts: 525
Reply 2 on: Jan 12, 2022
YES! Correct, THANKS for helping me on my review

blakcmamba

  • Member
  • Posts: 335
Reply 3 on: Yesterday
Excellent

« previous next »
 

Did you know?

Urine turns bright yellow if larger than normal amounts of certain substances are consumed; one of these substances is asparagus.

Did you know?

The effects of organophosphate poisoning are referred to by using the abbreviations “SLUD” or “SLUDGE,” It stands for: salivation, lacrimation, urination, defecation, GI upset, and emesis.

Did you know?

Cancer has been around as long as humankind, but only in the second half of the twentieth century did the number of cancer cases explode.

Did you know?

As many as 28% of hospitalized patients requiring mechanical ventilators to help them breathe (for more than 48 hours) will develop ventilator-associated pneumonia. Current therapy involves intravenous antibiotics, but new antibiotics that can be inhaled (and more directly treat the infection) are being developed.

Did you know?

The largest baby ever born weighed more than 23 pounds but died just 11 hours after his birth in 1879. The largest surviving baby was born in October 2009 in Sumatra, Indonesia, and weighed an astounding 19.2 pounds at birth.

Conduction of the action potential along an axon. Conduction of the action potential along an axon.
) Intradermal drug administration: (c) the needle is inserted, bevel up at 10–15° ) Intradermal drug administration: (c) the needle is inserted, bevel up at 10–15°
The approval of a new drug is a four-stage process: (1) preclinical investigation, (2) clinical inve The approval of a new drug is a four-stage process: (1) preclinical investigation, (2) clinical inve
Effect of pH on drug absorption: (a) A weak acid such as aspirin (ASA) is in a nonionized form in an ... Effect of pH on drug absorption: (a) A weak acid such as aspirin (ASA) is in a nonionized form in an ...
Plasma protein binding and drug availability. (a) Drug exists in a free state or bound to plasma ... Plasma protein binding and drug availability. (a) Drug exists in a free state or bound to plasma ...
Warfarin An anticoagulant drug given to prevent blood from clotting Warfarin An anticoagulant drug given to prevent blood from clotting
Video: Insulin (glucose uptake by body cells), glycogenesis and lipogenesis

For a complete list of videos, visit our video library