Answer to Question 1
ANS: B
COPD is the most common current indication for lung transplantation.
Answer to Question 2
ANS: B
Difficulties with intravenous augmentation therapy include the substantial expense (approxi-mately 100,000 per year), the inconvenience of frequent intravenous infusions for life, and the infusion itself, which confers a theoretical risk of transmitting a blood-borne infection.