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Drug-induced pharmacodynamic effects manifested in older adults include drug-induced renal toxicity, which can be a major factor when these adults are experiencing other kidney problems.
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It is believed that the Incas used anesthesia. Evidence supports the theory that shamans chewed cocoa leaves and drilled holes into the heads of patients (letting evil spirits escape), spitting into the wounds they made. The mixture of cocaine, saliva, and resin numbed the site enough to allow hours of drilling.
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Drying your hands with a paper towel will reduce the bacterial count on your hands by 45–60%.
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The horizontal fraction bar was introduced by the Arabs.
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About 100 new prescription or over-the-counter drugs come into the U.S. market every year.