A psychiatricmental health nurse is aware that variations in ...

[tth]

A psychiatricmental health nurse is aware that variations in pharmacokinetics can greatly affect individuals' responses to drugs. Which of the following clients may experience disruptions in the normal elimination of a drug?
 
  A) A client who has been diagnosed with vascular dementia
  B) A client who has a genetic alteration in her P450 liver enzyme system
  C) A client who has ingested a large amount of free water
  D) A client who has been diagnosed with chronic renal failure

Question 2

The nurse is developing a plan of care for a client who is taking two antidepressants and one anxiolytic medication for treatment of depression and anxiety. Which of the following represents a realistic goal?
 
  A) The client will be able to eliminate the anxiolytic medication after learning stress management techniques.
  B) The client will be able to eliminate two of the three medications within 1 year.
  C) The client will express satisfaction with his medication regimen.
  D) The client will experience no side effects.

[Tonny]

Answer to Question 1

Ans: D
Feedback:
Most drugs are eliminated by either the kidneys or gastrointestinal tract. As such, clients who have renal failure typically experience significant disruptions in elimination. The P450 liver enzyme system affects metabolism, not elimination.

Answer to Question 2

Ans: C
Feedback:
Evaluation of a client's medication regimen involves reviewing the drug's efficacy in improving functioning, discussing the client's subjective perception of response to medication, and regularly monitoring perceived response, feelings about the medication, and potential difficulties.