A severely depressed patient has been prescribed clomipramine ...

[bobthebuilder]

A severely depressed patient has been prescribed clomipramine (Anafranil). For which medication side effects should the patient be monitored?
 
  a. Excess salivation and drooling
  b. Muscle rigidity and restlessness
  c. Polyuria and coarse hand tremors
  d. Orthostatic hypotension and constipation

Question 2

Which of these statements made by a patient taking the MAOI phenelzine (Nardil) would warrant further instruction?
 
  a. I often forget to wear sunscreen when I go outside.
  b. I need to restrict the amount of sodium in my diet.
  c. I should not use over-the-counter cold medications.
  d. I usually order liver and onions when my wife and I eat out.

[Moriaki]

Answer to Question 1

ANS: D
Alpha1 blockade produces orthostatic hypotension, and cholinergic blockade produces con-stipation. Mild tremors and urinary retention may occur. Drooling and excessive salvation may occur with SSRIs. Muscle rigidity and restlessness may occur with antipsychotics.

Answer to Question 2

ANS: D
MAOIs require patients to observe a tyramine-free diet to prevent hypertensive crisis. Liver is a food that contains large amounts of tyramine. The remaining options have no relevance for MAOI therapy.

[bobthebuilder]

Excellent

[covalentbond]

Gracias!