In 1864, the first barbiturate (barbituric acid) was synthesized.
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In 1844, Charles Goodyear obtained the first patent for a rubber condom.
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Lower drug doses for elderly patients should be used first, with titrations of the dose as tolerated to prevent unwanted drug-related pharmacodynamic effects.
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The first oral chemotherapy drug for colon cancer was approved by FDA in 2001.
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The average adult has about 21 square feet of skin.