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Certain topical medications such as clotrimazole and betamethasone are not approved for use in children younger than 12 years of age. They must be used very cautiously, as directed by a doctor, to treat any child. Children have a much greater response to topical steroid medications.
Pope Sylvester II tried to introduce Arabic numbers into Europe between the years 999 and 1003, but their use did not catch on for a few more centuries, and Roman numerals continued to be the primary number system.
In the United States, there is a birth every 8 seconds, according to the U.S. Census Bureau's Population Clock.
On average, someone in the United States has a stroke about every 40 seconds. This is about 795,000 people per year.
The first oral chemotherapy drug for colon cancer was approved by FDA in 2001.