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Long-term mental and physical effects from substance abuse include: paranoia, psychosis, immune deficiencies, and organ damage.
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Disorders that may affect pharmacodynamics include genetic mutations, malnutrition, thyrotoxicosis, myasthenia gravis, Parkinson's disease, and certain forms of insulin-resistant diabetes mellitus.
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Interferon was scarce and expensive until 1980, when the interferon gene was inserted into bacteria using recombinant DNA technology, allowing for mass cultivation and purification from bacterial cultures.
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By definition, when a medication is administered intravenously, its bioavailability is 100%.
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There are more nerve cells in one human brain than there are stars in the Milky Way.