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Disorders that may affect pharmacodynamics include genetic mutations, malnutrition, thyrotoxicosis, myasthenia gravis, Parkinson's disease, and certain forms of insulin-resistant diabetes mellitus.
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Studies show that systolic blood pressure can be significantly lowered by taking statins. In fact, the higher the patient's baseline blood pressure, the greater the effect of statins on his or her blood pressure.
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People with high total cholesterol have about two times the risk for heart disease as people with ideal levels.
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Medication errors are more common among seriously ill patients than with those with minor conditions.
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Excessive alcohol use costs the country approximately $235 billion every year.