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Excessive alcohol use costs the country approximately $235 billion every year.
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In 1864, the first barbiturate (barbituric acid) was synthesized.
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In 1885, the Lloyd Manufacturing Company of Albany, New York, promoted and sold "Cocaine Toothache Drops" at 15 cents per bottle! In 1914, the Harrison Narcotic Act brought the sale and distribution of this drug under federal control.
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Human kidneys will clean about 1 million gallons of blood in an average lifetime.
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Intradermal injections are somewhat difficult to correctly administer because the skin layers are so thin that it is easy to accidentally punch through to the deeper subcutaneous layer.